Duration: 4h 3m
Lectures: 20
Research-based: Yes
When: 15th June
How: Prerecorded Online Lectures
Learn at your pace, complete the course anytime, anywhere!
A real-life project-based hands-on computational development of a chimeric vaccine against Dracunculus medinesis
Learn, practice, apply and research on real-life computational vaccine development
Based Upon Published Research
This hands-on guide content and video lectures are created by the same authors.
Publication: Rational design of multimeric based subunit vaccine against Mycoplasma pneumonia: Subtractive proteomics with immunoinformatics framework
Journal: Infection, Genetics and Evolution, Volume 91, 2021
Link: view here
Authors: Marvah Mahmood, Anam Javaid, Farah Shahid, Usman Ali Ashfaq
Key facts
Opening Date of Registration: May 8th, 2021
Commencement of Course: 15th June, 2021
(Netflix-style Streaming, Complete the course anytime! 1 Year Access - Learn at your pace)
No prior Bioinformatics knowledge required
100% money-back guarantee
Based on published research
For beginners and advanced learners alike
Computational Vaccine Discovery Pipeline
Immune System Simulation
Prediction of Epitopes
Modeling of a Chimeric Vaccine
Molecular Docking and Molecular Dynamics Studies with TLR4
Learn Complete Immunoinformatics Approach for Computational Vaccine Development
Why vaccines are important and how Immunoinformatics & Bioinformatics can help us fight pandemics
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Vaccines are the most cost-effective public health interventions.
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Vaccines are biological substances that are utilized to stimulate antibody production within the body of an organism to provide active immunity against foriegn organisms, mostly viruses and bacteria.
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Chimeric vaccines are types of recombinant vaccines, produced by substituting genes from the target pathogen in a closely related organism, for similar genes.
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Chimeric vaccines are useful in studying infectious diseases, including many neglected diseases.
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Immuno-Bioinformatics is being extensively used in designing B-, T-cell epitopes, vaccines, antibodies, adjuvants, diagnostic kits, and therapeutics.
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Bioinformatics is also involved in medication development aimed at bio-productive and pharmaceutical/vaccine development.
What Will You Learn
Scope, Skills and Topics
We offer 100% guarantee that you will gain skills and understanding on how to develop a vaccine against the pathogen of your choice. If you're not satisfied with the content, we offer 100% money-back guarantee!
In this pre-recorded, hands-on guide on developing vaccines against infectious pathogens, you’ll be learning a huge set of Bioinformatics and Immunoinformatics skills that can help you in designing vaccines against pathogens.
The practical and theoretical skill set that you’ll develop in this course are as follows
Protein Databases
Molecular Docking and Molecular Dynamics
Population Genetic Studies
Prediction of B-, T-cell Epitopes
Computational Development of Chimeric Vaccine
Stability Analysis of Chimeric Vaccine
Case-Study and Real Life Research
In this course, you will be learning how to develop a vaccine against Dracunculus medinesis which causes guinea worm disease in humans.
The video lecture series will take you from the basics such as proteome retrieval of Dracunculus medinesis and all the way to computational development of a chimeric vaccine.
Computational Vaccine Discovery Pipeline
Retrieval of Proteome, Antigenicity and Location Prediction
Prediction and Evaluation of cytotoxic T-Lymphocytes (CTL) Epitopes
Prediction and assessment of Helper T-Lymphocytes (HTL) Epitopes
Prediction and assessment of Linear B-Lymphocytes (LBL) Epitopes
Molecular Docking Studies
Estimation of Population Coverage
Mapping of Vaccine Construct
Codon optimization and In Silico Cloning
Immune Simulation
Molecular Dynamic Simulation
Docking between vaccine protein & TLR4 receptor
Screening of B Cell Epitopes Disulfide Engineering of Vannice protein
Tertiary Structure Prediction, Refinement & Validation
Primary & Secondary Structure Prediction & Analysis
Key dates
Enroll anytime, anywhere and start learning at your pace!
Netflix-style Streaming, Complete the course anytime! 1 Year Access)
Our philosophy is that you learn real-life research
Learning should be at your convenience
We believe that not everyone is a fast learner especially when it comes to Bioinformatics, so our courses and workshops are designed in such a way that you learn at your own pace, during any time of the day and any number of times. You will get access to this course for 1 year!
Everything Online, For Everyone
Whether you're a beginner in Bioinformatics, an experimental biologist or a researcher from any field of biology, our course will help you greatly in developing a vaccine.
Learn effectively with well-curated materials
For an optimal learning experience we carefully prepare our learning materials and example data. So, you comprehend how your newly gained skills can help you do great research!
Course Modules
You will be able to learn how to computationally develop a vaccine against any pathogenic microbe!
Module 1
Learn various Protein Bioinformatics databases for the retrieval and analysis of pathogen proteomes, protein structures, protein families and other datasets required for vaccine development.
Module 2
Learn different Bioinformatics tools, servers, databases for prediction of B and T cell epitopes for filtration of pathogenically important regions of the pathogenic microbe.
Module 3
Learn highly utilized and most efficient bioinformatics tools and servers for 3D structure prediction of chimeric vaccines, peptides and proteins.
Module 4
Learn highly efficient and accurate tools and web servers for the visualization and evaluation of 3D structures of the chimeric modelled vaccines for their assessment.
Segment 5
Learn molecular docking against TLR4 protein structures of the developed vaccines and assess its stability through molecular dynamics and simulations.
Segment 6
Learn how to do population genetics and immune simulation analysis of the developed vaccine to predict its usability among the masses and its response within the body, i.e., immune system.
Course Contents
Some Highlights
Requirements
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You don't need any prior Bioinformatics, programming or immunoinformatiocs knowledge or skills for this course, we'll take care of that and teach you the required topics!
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Basic immunology background is a plus point, however, if you lack this knowledge, during the course, you'll be taught the basics as well.
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This course is for both beginners and professionals alike, anyone with biology background can avail this course.
Target Audience
The target audience for this Fighting Pandemics: A Complete Guide On Developing Chimeric Vaccines Against Infectious Pathogens workshop are biologists, beginner or intermediate Bioinformaticians or data analysts with no or little experience in applications of computational bioinformatics and bioinformatics pipelines for protein analysis.
However, a superficial understanding of molecular biology and immunology is expected from you before you join the course.
This hands-on guide will help you properly to understand Immunoinformatis and Bioinformatics, and it is quite easy to get started in, even if you lack a proper understanding of the underlying concepts of Bioinformatics databases, servers, tools and the algorithms working behind them.