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NCBI Genome

BioCodeKb - Bioinformatics Knowledgebase

NCBI's Genome resources include information on large-scale genomics projects, genome sequences and assemblies, and mapped annotations, such as variations, markers and data from epigenomics studies.

The Genome database contains sequence and map data from the whole genomes of over 1000 species or strains. The genomes show both completely sequenced genomes and those with sequencing in-progress. All three main domains of life (bacteria, archaea, and eukaryota) are represented, as well as many viruses, phages, viroids, plasmids, and organelles.

Sources that support our data at Genome in NCBI are;

Genome: contain information about organisms' genomes

Assembly: genomic assembly statistics

Nucleotide: genome sequences in the Nucleotide repository

SRAhigh-throughput DNA sequences

GSS: genome survey sequences

Genome BLAST: sequence search tool for genome sequences

Other custom resources at NCBI are;

  • Human Genome

  • Microbes

  • Organelles

  • Viruses

  • Prokaryotic reference genomes

A recent release of the GenBank database, version 210.0 (released on October 15, 2015), Genome contains over 621 billion base pairs from 2,557 eukaryal genomes, 432 archaeal genomes, and 7,474 bacterial genomes, as well as tens of thousands of viral genomes, organellar genomes, and plasmid sequences

Functional Genomics

GEO DataSets: functional genomics study data

GEO2R: identifies differentially expressed genes in GEO datasets

Genome Annotation and Analysis are aslo done at NCBI of following genoms;

  • Eukaryotic Genome Annotation

  • Prokaryotic Genome Annotation

  • Pairwise Sequence Comparison

Genome Tools

  • BLAST the Human Genome

  • Microbial Nucleotide BLAST

Basic Features of Genome 

  • Loading a Genome

  • Six Frame Translations

  • Search and View a Gene

  • Move and Dock Windows

  • Phylogenetic Trees

  • Window Masker

  • Import BAM and Export Selected Alignments

  • Using ProSplign

  • Multiple Sequence Aligners in Genome Workbench

  • Genome Workbench: The Update Sequence Feature

The history of Genome at NCBI is intimately tied to the history of GenBank and RefSeq. NCBI’s early commitment to reliably and robustly support the simple request to download, view, or analyze a genome resulted in a large suite of resources, tools, and shareable code-base.Complete Human Genome Resource is also present at NCBI.

To search any genome of organism listed at Genome database in NCBI, we search for its name with selecting the Genome database. A complete reference page for that organism is opened containing genomic information, genomic features, taxonomic importance, downloaded resources, lineages, NCBI annotations, Releases of that organism, publications and all the complete genome information in the form of chromosomes.

We can obtain the genomic sequence, gene marker sequence by setting the bp numbers in the change region show option according to our need at Gene Table option.

To use the download service, run a search in Assembly, use facets to refine the set of genome assemblies of interest, open the "Download Assemblies" menu, choose the source database (GenBank or RefSeq), choose the file type, then click the Download button to start the download for that genome.


Need to learn more about NCBI Genome and much more?

To learn Bioinformatics, analysis, tools, biological databases, Computational Biology, Bioinformatics Programming in Python & R through interactive video courses and tutorials, Join BioCode.

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